House
10.0(193 Reviews)
2 Bedrooms
6 Guests
Oceanfront
Parking
Pool
Ocean View
AU $637/Night
7 Nights - AU $4,462
Panhandle Key Villa Rentals
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Compare Villas, Resorts, & Rentals in Panhandle Key
10.0
House
10.0(2 Reviews)
3 Bedrooms
6 Guests
Breakfast- Parking
- Pool
Spa
AU $1,385/Night
7 Nights - AU $9,693
AU $265/Night
7 Nights - AU $1,853
House
10.0(193 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $518/Night
7 Nights - AU $3,622
AU $3,583/Night
7 Nights - AU $25,084
Boat Rental
9.0(176 Reviews)
1 Bedroom
2 Guests
- Parking
- Pool
Kitchen
Air Conditioner
AU $393/Night
7 Nights - AU $2,755
House
10.0(152 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $506/Night
7 Nights - AU $3,545
Apartment
9.5(9 Reviews)
3 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $271/Night
7 Nights - AU $1,898
House
9.0(14 Reviews)
2 Bedrooms
4 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $658/Night
7 Nights - AU $4,605
Cottage
10.0(141 Reviews)
1 Bedroom
2 Guests
- Parking
- Ocean View
Balcony/Terrace
View
AU $514/Night
7 Nights - AU $3,596
House
9.5(4 Reviews)
2 Bedrooms
4 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $464/Night
7 Nights - AU $3,251
Villa
10.0(126 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $634/Night
7 Nights - AU $4,438
House
9.5(4 Reviews)
2 Bedrooms
5 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $441/Night
7 Nights - AU $3,090
House
10.0(103 Reviews)
2 Bedrooms
5 Guests
- Oceanfront
Hot Tub- Parking
- Pool
AU $1,106/Night
7 Nights - AU $7,745
House
10.0(95 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $720/Night
7 Nights - AU $5,038
Villa
10.0(95 Reviews)
2 Bedrooms
4 Guests
- Oceanfront
- Parking
- Ocean View
- Balcony/Terrace
AU $502/Night
7 Nights - AU $3,512
House
10.0(91 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $772/Night
7 Nights - AU $5,405
House
10.0(90 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $555/Night
7 Nights - AU $3,886
House
10.0(72 Reviews)
2 Bedrooms
8 Guests
Private Pool- Oceanfront
- Parking
- Pool
AU $532/Night
7 Nights - AU $3,724
House
10.0(63 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $352/Night
7 Nights - AU $2,467
Condo
10.0(62 Reviews)
2 Bedrooms
4 Guests
- Private Pool
- Oceanfront
- Hot Tub
- Parking
AU $728/Night
7 Nights - AU $5,096
Condo
10.0(62 Reviews)
2 Bedrooms
6 Guests
- Parking
- Pool
- Ocean View
- Balcony/Terrace
AU $363/Night
7 Nights - AU $2,543
House
10.0(61 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $631/Night
7 Nights - AU $4,419
House
10.0(59 Reviews)
2 Bedrooms
6 Guests
- Oceanfront
- Parking
- Pool
- Ocean View
AU $711/Night
7 Nights - AU $4,974
About Panhandle Key Vacation Rentals
There are more than 1919 incredible getaway rentals that are available in Panhandle Key. These choices include villas, hotels, and other rental options. Browse from a massive selection of luxury amenities at great prices, providing you with the dream spot to base your next vacation. Relax with BedroomVillas and uncover great stays in Panhandle Key.
BedroomVillas helps you find the ideal holiday rental to create lifetime travel memories in Panhandle Key. Prices listed are often found to be discounted versus the rack rates. Just search for your destination and secure your perfect place to stay today.
Hotels in Panhandle Key
- Prices for a holiday home in Panhandle Key start at AU $146
- Top rated vacation home in Panhandle Key is Islamorada home in Anglers Reef with Ocean Views, Dock, Com Pool & Private Beach
- Most popular short term in Panhandle Key is Chesapeake Beach Resort
- Cheapest place to stay in Panhandle Key is Turnkey Modern Studio in the Upper Keys – Stylish, Bright & Fully Equipped!
- Most expensive holiday rental in Panhandle Key is Chateau On The Ocean - The Southernmost Shangrila
Recently Booked Hotels, Resorts, or Rentals in Panhandle Key
Frequently Asked Questions About Panhandle Key?
What are the top hotels or resorts in Panhandle Key?
We provide an array of great vacation destinations in Panhandle Key. If you are looking to stay in or around the Panhandle Key area, make sure to browse our options to find a premium rental location in a top vacation destination. Whether it is a few nights, a week, or more, we've got the luxury stays that rank among the Top Vacation Rentals in Panhandle Key:
- Islamorada home in Anglers Reef with Ocean Views, Dock, Com Pool & Private Beach
- OCEANSIDE ANGLERS REEF HOME- Gated community- Pool, Dock, Private Beach
- The Caribbean Resort
- Beautiful Island Home in Anglers Reef! Ocean front community. Pool & boat slip.
- WATERFRONT FISHING COTTAGE/DOCKAGE + Walking distance to world famous Lorelei
- 5 bedroom - Deep Dockage & Heated Pool in Islamorada.
- Serenity by the Sea! Anglers Reef with Boat Slip Available!
- 4 Bedroom House in Angler's Reef, Includes 31' Boat Slip. Islamorada, FL
- Private Oceanfront: Heated Pool, Paddleboards & Kayaks - 180 degree ocean views
- Beautiful Ocean View in Angler's Reef with View of Sand Bar/Boat slip
How many hotels, resorts, or rentals are available in Panhandle Key?
BedroomVillas offers a consistent supply of new options, combined with established great stays in top areas. Currently, the number of properties listed by BedroomVillas in 2026 is over 1919 in the Panhandle Key area, and that number rises every day. By combining listings from multiple websites and travel providers, BedroomVillas can provide you with a diverse amount of choices of the best luxury stays in Panhandle Key.
Nearby Neighborhood (12)
| Neighborhood | Property Count |
|---|---|
| Venetian Shores Rental Villas and Private Getaways in Florida | 34 |
| Lower Matecumbe Beach Rental Villas and Private Getaways in Florida | 25 |
| Indian Waterways Rental Villas and Private Getaways in Florida | 661 |
| Sunshine Estates Rental Villas and Private Getaways in Florida | 1184 |
| Toll Gate Shores Rental Villas and Private Getaways in Florida | 329 |
| White Marlin Beach Rental Villas and Private Getaways in Florida | 341 |
| Seabreeze Trailer Park Rental Villas and Private Getaways in Florida | 833 |
| Plantation Tropical Park Rental Villas and Private Getaways in Florida | 1170 |
| Plantation by the Sea Rental Villas and Private Getaways in Florida | 745 |
| Plantation Lake Estates Rental Villas and Private Getaways in Florida | 709 |
| Coral Cove Rental Villas and Private Getaways in Florida | 643 |
| Bonefish Bay Rental Villas and Private Getaways in Florida | 346 |
